Evaluation of prevalence of MDR-TB incidences in 24-beds MDR-TB hospital-Mazar-e-sharif -2024

Abstract

Tuberculosis is a chronic, contagious and one of the ten murderous diseases all over the world. Getting resistant of tuberculosis is because of using poor medicated regime, inappropriate medicated adherence & using ineffective drugs. The most resistance is against firs line treatment drugs like rifampicin and isoniazid. This research has done in the 24-beds MDR-TB hospital. Aim of this research is the investigating of MDR-TB incidences in 24-beds multi-drug resistant hospital-Mazar-e-sharif city. This research is quantitative – descriptive research, which has done by cross-sectional study in the time of one year (from beginning of 1403 up to end) in 24 beds MDR-TB hospital Mazar e sharif by taking information from registration system and talking with responsible of the hospital. findings of the research show that MDR-TB incidences are 155 patients, (5.98%) of the total (2588) cases of tuberculosis. The most cases of MDR-TB are female (100) people (68%) and less cases Among men (32%). Most MDR-TB cases among the patients which are aged between 18-40 years (48.38%).  The many cases (65.8%) of MDR-TB is from Mazar e sharif city.  Resistance is against rifampicin and isoniazid in the number of 152 (97%). main reason of resistance is inappropriate adherence representing a percentage of 54.83%. MDR-Tuberculosis is a serious health problem in this city that complicates the process of the treatment of this disease. MDR-TB is the 5.98% of the total cases of tuberculosis. Most infected of MDR-TB is women representing percentage of 68%. Resistance is the most against Isoniazid and rifampicin drugs and causes like no medicates adherence, utilizing of poor medicated regime, bad economics situation and using the ineffective drug are the reasons of the resistance. Notifying the patients by doctors on how lethal is the MDR-TB, complete medicated adherence, complete medicated adherence, using good treatment regime of drug and admitting of patient during the treatment for decreasing of the cases should be done, will be effective.